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Meta-analysis finds remote cardiac rehabilitation matches or exceeds centre-based care for heart failure patients

A meta-analysis of eight randomised trials finds mobile-health-supported remote or hybrid cardiac rehabilitation performs as well as, or better than, centre-based rehabilitation on exercise capacity in heart failure, though certainty is low to moderate.

1 min read Meta-analysis NEW

A systematic review and meta-analysis in JMIR mHealth and uHealth pooled eight randomised controlled trials (1,368 patients) comparing mobile-health-supported remote, virtual or hybrid cardiac rehabilitation against usual care or centre-based cardiac rehabilitation in patients with heart failure, most with reduced ejection fraction [Meta-analysis]. Against centre-based rehabilitation, the remote/hybrid model showed a statistically significant greater improvement in peak oxygen uptake, though this was based on a limited number of trials; against usual care, it was associated with improved six-minute walk distance. Certainty of evidence ranged from low to moderate throughout.

The authors are explicit that superiority, equivalence or non-inferiority against centre-based rehabilitation cannot be concluded from the current evidence, given the small number of trials in that specific comparison. No intervention-related deaths or serious adverse events were reported, but sparse events and short follow-up limit what can be concluded about safety.

For heart failure services facing centre-based cardiac rehabilitation capacity constraints, this supports remote or hybrid delivery as a credible option for some patients, though the evidence does not yet support it as a wholesale replacement for centre-based rehabilitation, and longer-term safety data remain limited.

Sources

  1. Shao K, Liu C, Li T, Qu H, Zhou H. Effects of Remote, Virtual, or Hybrid Cardiac Rehabilitation Supported by mHealth in Patients With Heart Failure: Systematic Review and Meta-Analysis. JMIR mHealth and uHealth. 2026;14:e90422. doi:10.2196/90422 PMID 42480049